Analysis of copper and zinc levels in the mucosal tissue and serum of oral submucous fibrosis patients

Background and Objectives:Although the pathogenesis of oral submucous fibrosis (OSMF) has been studied, it remains unclear whether or not this illness might progress to malignancy. The may be better understood by measuring copper zinc levels in tissue serum from these people. Because widespread cultural social usage areca nuts India, a research was conducted investigate their concentrations population. Methods:Twenty people with OSMF twenty without were studied case-control fashion. Copper measured 40 patients' tissues blood using colorimetry. Compared concentration 25.18 4.92 g/gm found group tissues, 4.31 1.13 g/gm. Zinc 0.92 0.18 g/ml 1.00 0.20 on average group. Interpretation conclusion:OSMF substantially different control (p = 0.009), as 0.001). There no statistically significant difference 0.35) 0.08) between experimental groups.